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Lieu C, Kennedy EB, Bergsland E, Berlin J, George TJ, Gill S et al (2019) Duration of Oxaliplatin-Containing Adjuvant Therapy for Stage III Colon Cancer, ASCO Clinical Practice Guideline

doi: 10.1016/j.semcancer.2019.12.019 82 ShenCLiMDuanYJiangXHouXXueFet al

They target healing through different but complementary pathways

The future lies in developing selective modulatorsboth inhibitors and potential activatorstailored to specific diseases and biological contexts, such as hormone-sensitive cancers, neuroinflammatory conditions, and metabolic syndromes